Brucina

[1]Philippe G, Angenot L, Tits M, Frédérich M. About the toxicity of some Strychnos species and their alkaloids. Toxicon. 2004; 44(4):405-416.

[2] Bruneton J. Farmacognosia, Fitoquímica, Plantas medicinales.2.ª ed.,  Espanha:ACRIBIA. 1993.

[3]Achappa B, Madi D, Raghavendra Babu YP,Mahalingam S. Rituals can kill – A fatal case of brucine poisoning. AMJ. 2012;5 (8):421­‐423.

[4] Yin W, Wang TS, Yin FZ, Cai BC. Analgesic and anti-inflmmatory properties of brucine and brucine N-oxide extracted from seeds of Strychnos nux-vomica. J Ethnopharmacol. 2003; 88:205–14.

[5] Oliva P, Aurilio C, Massimo F, Grella A, Maione S, Grella E, Scafuro M, Rossi F, Berrino L. The antinociceptive effectof tramadol in the formalin test is mediated by the serotonergic component.European Journal of Pharmacology. 2002; 445 :179–185.

[6]Chen J, Hu W, Qu Y, Dong J, Gu W, Gao Y, Fang Y, Fang F, Chen Z, Cai B. Evaluation of the pharmacodynamics and pharmacokinetics of brucine following transdermal administration. Fitoterapia. 2013 ; 86: 193-201.

[7]Saraswati S, Alhaider AA, Agrawal SS. Anticarcinogenic effect of brucine in diethylnitrosamine initiated and phenobarbital-promoted hepatocarcinogenesis in rats. Chemico-Biological Interactions. 2013; 206: 214–221.

[8] Shu G, Mi X, Cai J, Zhang X, Yin W, Yang X, Li Y, Chen L, Deng X. Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn.,represses hepatocellular carcinoma cell migration and metastasis: The role of hypoxia inducible factor 1 pathway. Toxicology Letters. 2013; 222: 91– 101.

[9]  Toxnet : http://chem.sis.nlm.nih.gov/chemidplus/rn/357-57-3 consultado a 27 de Maio de 2014.

[10] CDC : http://www.cdc.gov/niosh/ipcsneng/neng1017.html consultado a 27 de Maio de 2014.

[11] Malone MH, John-Allan KMS, Bejar E. Brucine lethality in mice. Journal of Ethnopharmacology. 1992; 35: 295-297.

[12] Gosselin RE, Smith RP, Hodge HC, Braddock JE. Clinical Toxicology of Commercial Products. Williams & Wilkins. 1984; 5: 1976 - 1783.

[13] Li X, et al. In vitro metabolism of brucine by human liver microsomes and its interactions with CYP substrates. Chemico-Biological Interactions. 2013; 204:140–143.

[14] Wang Z, Zhao J, Xing J, He Y, Guo D. Analysis of Strychnine and Brucine in Postmortem Specimens by RP-HPLC: A Case Report of Fatal Intoxication. Journal of Analytical Toxicology.2004;28(2):141-144.

[15] Naik BS, Chakrapani M. A rare case of brucine poisoning complicated by rhabdomyolysis and acute renal failure. Malays J Pathol. 2009;31:67–69.